The presynaptic component of the serotonergic system is required for clozapine's efficacy.
Yadav PN; Abbas AI; Farrell MS; Setola V; Sciaky N; Huang XP; Kroeze WK; Crawford LK; Piel DA; Keiser MJ; Irwin JJ; Shoichet BK; Deneris ES; Gingrich J; Beck SG; Roth BL; Neuropsychopharmacology: Official Publication Of The American College Of Neuropsychopharmacology, 2011, vol. 36, issue 3, p 638, ISSN 1740634x. ISBN 1740634x.

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