Membrane protein stability can be compromised by detergent interactions with the extramembranous soluble domains.
Yang Z; Wang C; Zhou Q; An J; Hildebrandt E; Aleksandrov LA; Kappes JC; DeLucas LJ; Riordan JR; Urbatsch IL; Hunt JF; Brouillette CG; Protein Science: A Publication Of The Protein Society, 2014, vol. 23, issue 6, p 769, ISSN 1469896x. ISBN 1469896x.

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