Zic2-associated holoprosencephaly is caused by a transient defect in the organizer region during gastrulation.
Warr N; Powles-Glover N; Chappell A; Robson J; Norris D; Arkell RM; Human Molecular Genetics, 2008, vol. 17, issue 19, p 2986, ISSN 14602083. ISBN 14602083.

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