The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation.
Nilsberth C; Westlind-Danielsson A; Eckman CB; Condron MM; Axelman K; Forsell C; Stenh C; Luthman J; Teplow DB; Younkin SG; Näslund J; Lannfelt L; Nature Neuroscience, 2001, vol. 4, issue 9, p 887, ISSN 10976256. ISBN 10976256.

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