The ubiquitin ligase COP1 is a critical negative regulator of p53.
Dornan, David; Wertz, Ingrid; Shimizu, Harumi; Arnott, David; Frantz, Gretchen D.; Downd, Patrick; O'Rourke, Karen; Koeppen, Hartmut; Dixit, Vishva M.; Nature, 2004, vol. 429, issue 6987, p 86, ISSN 00280836. ISBN 00280836.

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