Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity.
Wolfe MS; Xia W; Ostaszewski BL; Diehl TS; Kimberly WT; Selkoe DJ; Nature, 1999, vol. 398, issue 6727, p 513, ISSN 00280836. ISBN 00280836.

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