Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein.
De Strooper B; Saftig P; Craessaerts K; Vanderstichele H; Guhde G; Annaert W; Von Figura K; Van Leuven F; Nature, 1998, vol. 391, issue 6665, p 387, ISSN 00280836. ISBN 00280836.

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