Congenital leptin deficiency is associated with severe early-onset obesity in humans.
Montague CT; Farooqi IS; Whitehead JP; Soos MA; Rau H; Wareham NJ; Sewter CP; Digby JE; Mohammed SN; Hurst JA; Cheetham CH; Earley AR; Barnett AH; Prins JB; O'Rahilly S; Nature, 1997, vol. 387, issue 6636, p 903, ISSN 00280836. ISBN 00280836.

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