Mode switching is the major mechanism of ligand regulation of InsP3 receptor calcium release channels.
Ionescu L; White C; Cheung KH; Shuai J; Parker I; Pearson JE; Foskett JK; Mak DO; The Journal Of General Physiology, 2007, vol. 130, issue 6, p 631, ISSN 00221295. ISBN 00221295.

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