Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice.
Lagace TA; Curtis DE; Garuti R; McNutt MC; Park SW; Prather HB; Anderson NN; Ho YK; Hammer RE; Horton JD; The Journal Of Clinical Investigation, 2006, vol. 116, issue 11, p 2995, ISSN 00219738. ISBN 00219738.

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