Circulating levels of IGF-1 directly regulate bone growth and density.
Yakar S; Rosen CJ; Beamer WG; Ackert-Bicknell CL; Wu Y; Liu JL; Ooi GT; Setser J; Frystyk J; Boisclair YR; LeRoith D; The Journal Of Clinical Investigation, 2002, vol. 110, issue 6, p 771, ISSN 00219738. ISBN 00219738.

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