We found a matchYour institution may have access to this item. Find your institution then sign in to continue.TitleExperimental and clinical evidence for loss of effect (tolerance) during prolonged treatment with antiepileptic drugs.AuthorsLöscher W; Schmidt DPublicationEpilepsia, 2006, Vol 47, Issue 8, p1253ISSN0013-9580Publication typearticleDOI10.1111/j.1528-1167.2006.00607.x